Ontology highlight
ABSTRACT:
SUBMITTER: Vaithianathan T
PROVIDER: S-EPMC2928634 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
American journal of physiology. Cell physiology 20100505 2
Ryanodine receptors (RyRs) regulate contractility in resistance-size cerebral artery smooth muscle, yet their molecular identity, subcellular location, and phenotype in this tissue remain unknown. Following rat resistance-size cerebral artery myocyte sarcoplasmic reticulum (SR) purification and incorporation into POPE-POPS-POPC (5:3:2; wt/wt) bilayers, unitary conductances of 110 +/- 8, 334 +/- 15, and 441 +/- 27 pS in symmetric 300 mM Cs(+) were usually detected. The most frequent (34/40 bilaye ...[more]