Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset.
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ABSTRACT:
SUBMITTER: Tritsch NX
PROVIDER: S-EPMC2928883 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Publications
Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset.
Tritsch Nicolas X NX Rodríguez-Contreras Adrián A Crins Tom T H TT Wang Han Chin HC Borst J Gerard G JG Bergles Dwight E DE
Nature neuroscience 20100801 9
We found rat central auditory neurons to fire action potentials in a precise sequence of mini-bursts before the age of hearing onset. This stereotyped pattern was initiated by hair cells in the cochlea, which trigger brief bursts of action potentials in auditory neurons each time they fire a Ca2+ spike. By generating theta-like activity, hair cells may limit the influence of synaptic depression in developing auditory circuits and promote consolidation of synapses. ...[more]
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