Visual exploration of genetic association with voxel-based imaging phenotypes in an MCI/AD study.
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ABSTRACT:
SUBMITTER: Kim S
PROVIDER: S-EPMC2928997 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Publications
Visual exploration of genetic association with voxel-based imaging phenotypes in an MCI/AD study.
Kim Sungeun S Shen Li L Saykin Andrew J AJ West John D JD
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 20090101
Neuroimaging genomics is a new transdisciplinary research field, which aims to examine genetic effects on brain via integrated analyses of high throughput neuroimaging and genomic data. We report our recent work on (1) developing an imaging genomic browsing system that allows for whole genome and entire brain analyses based on visual exploration and (2) applying the system to the imaging genomic analysis of an existing MCI/AD cohort. Voxel-based morphometry is used to define imaging phenotypes. ...[more]
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