Ontology highlight
ABSTRACT:
SUBMITTER: Antczak P
PROVIDER: S-EPMC2929951 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Antczak Philipp P Ortega Fernando F Chipman J Kevin JK Falciani Francesco F
PloS one 20100827 8
The identification of predictive biomarkers is at the core of modern toxicology. So far, a number of approaches have been proposed. These rely on statistical inference of toxicity response from either compound features (i.e., QSAR), in vitro cell based assays or molecular profiling of target tissues (i.e., expression profiling). Although these approaches have already shown the potential of predictive toxicology, we still do not have a systematic approach to model the interaction between chemical ...[more]