Ontology highlight
ABSTRACT:
SUBMITTER: Poulos AM
PROVIDER: S-EPMC2930410 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Poulos Andrew M AM Ponnusamy Ravikumar R Dong Hong-Wei HW Fanselow Michael S MS
Proceedings of the National Academy of Sciences of the United States of America 20100802 33
The basolateral amygdala (BLA) is thought to be essential for fear learning. However, extensive training can overcome the loss of conditional fear evident following lesions and inactivation of the BLA. Such results suggest the existence of a primary BLA-dependent and a compensatory BLA-independent neural circuit. We tested the hypothesis that the bed nuclei of the stria terminalis (BST) provides this compensatory plasticity. Using extensive context-fear conditioning, we demonstrate that combined ...[more]