Ontology highlight
ABSTRACT:
SUBMITTER: Carpenter-Hyland EP
PROVIDER: S-EPMC2930446 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Carpenter-Hyland Ezekiel P EP Plummer Thane K TK Vazdarjanova Almira A Blake David T DT
Proceedings of the National Academy of Sciences of the United States of America 20100730 33
Models of learning-dependent sensory cortex plasticity require local activity and reinforcement. An alternative proposes that neural activity involved in anticipation of a sensory stimulus, or the preparatory set, can direct plasticity so that changes could occur in regions of sensory cortex lacking activity. To test the necessity of target-induced activity for initial sensory learning, we trained rats to detect a low-frequency sound. After learning, Arc expression and physiologically measured n ...[more]