Ontology highlight
ABSTRACT:
SUBMITTER: Sezgin E
PROVIDER: S-EPMC2932829 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Sezgin Efe E Jabs Douglas A DA Hendrickson Sher L SL Van Natta Mark M Zdanov Alexander A Lewis Richard Alan RA Smith Michael W MW Troyer Jennifer L JL O'Brien Stephen J SJ
The Journal of infectious diseases 20100801 4
<h4>Background</h4>Cytomegalovirus (CMV) retinitis is a common opportunistic infection among patients with AIDS and still causes visual morbidity despite the wide spread usage of highly active antiretroviral therapy (HAART). The ubiquitous CMV pathogen contains a human interleukin-10 (IL-10) homolog in its genome and utilizes it to evade host immune reactions through an IL-10 receptor mediated immune-suppression pathway.<h4>Methods</h4>Effects of IL-10R1, IL-10 and previously described AIDS rest ...[more]