Ontology highlight
ABSTRACT:
SUBMITTER: Harjes CE
PROVIDER: S-EPMC2933658 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Harjes Carlos E CE Rocheford Torbert R TR Bai Ling L Brutnell Thomas P TP Kandianis Catherine Bermudez CB Sowinski Stephen G SG Stapleton Ann E AE Vallabhaneni Ratnakar R Williams Mark M Wurtzel Eleanore T ET Yan Jianbing J Buckler Edward S ES
Science (New York, N.Y.) 20080101 5861
Dietary vitamin A deficiency causes eye disease in 40 million children each year and places 140 to 250 million at risk for health disorders. Many children in sub-Saharan Africa subsist on maize-based diets. Maize displays considerable natural variation for carotenoid composition, including vitamin A precursors alpha-carotene, beta-carotene, and beta-cryptoxanthin. Through association analysis, linkage mapping, expression analysis, and mutagenesis, we show that variation at the lycopene epsilon c ...[more]