Ontology highlight
ABSTRACT:
SUBMITTER: Garry D
PROVIDER: S-EPMC2935499 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Garry Deirdre D Hansen Ronald M RM Moskowitz Anne A Elias Ellen R ER Irons Mira M Fulton Anne B AB
Documenta ophthalmologica. Advances in ophthalmology 20100504 2
<h4>Purpose</h4>To evaluate cone and cone-driven retinal function in patients with Smith-Lemli-Opitz syndrome (SLOS), a condition characterized by low cholesterol. Rod and rod-driven function in patients with SLOS are known to be abnormal.<h4>Methods</h4>Electroretinographic (ERG) responses to full-field stimuli presented on a steady, rod suppressing background were recorded in 13 patients who had received long-term cholesterol supplementation. Cone photoresponse sensitivity (S(CONE)) and satura ...[more]