Discovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches.
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ABSTRACT:
SUBMITTER: Brinkmeier ML
PROVIDER: S-EPMC2935795 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Publications
Discovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches.
Brinkmeier Michelle L ML Davis Shannon W SW Carninci Piero P MacDonald James W JW Kawai Jun J Ghosh Debashis D Hayashizaki Yoshihide Y Lyons Robert H RH Camper Sally A SA
Genomics 20090211 5
We report a catalog of the mouse embryonic pituitary gland transcriptome consisting of five cDNA libraries including wild type tissue from E12.5 and E14.5, Prop1(df/df) mutant at E14.5, and two cDNA subtractions: E14.5 WT-E14.5 Prop1(df/df) and E14.5 WT-E12.5 WT. DNA sequence information is assembled into a searchable database with gene ontology terms representing 12,009 expressed genes. We validated coverage of the libraries by detecting most known homeobox gene transcription factor cDNAs. A to ...[more]
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