Ontology highlight
ABSTRACT:
SUBMITTER: Konno T
PROVIDER: S-EPMC2940508 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Konno Toshihiro T Graham Amanda R AR Rempel Lea A LA Ho-Chen Jennifer K JK Alam S M Khorshed SM Bu Pengli P Rumi M A Karim MA Soares Michael J MJ
Endocrinology 20100721 9
Early pregnancy loss is common and can be caused by a range of factors. The Brown Norway (BN) rat exhibits reproductive dysfunction characterized by small litter size and pregnancy failure and represents a model for investigating early pregnancy loss. In this study, we investigated the establishment of pregnancy in the BN rat and gained insight into mechanisms causing its subfertility. Early stages of BN uteroplacental organization are unique. The BN primordial placenta is restricted in its deve ...[more]