Ontology highlight
ABSTRACT:
SUBMITTER: Guo F
PROVIDER: S-EPMC2940828 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Guo Fuzheng F Maeda Yoshiko Y Ma Joyce J Xu Jie J Horiuchi Makoto M Miers Laird L Vaccarino Flora F Pleasure David D
The Journal of neuroscience : the official journal of the Society for Neuroscience 20100901 36
Previous studies have shown that oligodendroglial progenitor cells (OPCs) can give rise to neurons in vitro and in perinatal cerebral cortex in vivo. We now report that OPCs in adult murine piriform cortex express low levels of doublecortin, a marker for migratory and immature neurons. Additionally, these OPCs express Sox2, a neural stem cell marker, and Pax6, a transcription factor characteristic of progenitors for cortical glutamatergic neurons. Genetic fate-mapping by means of an inducible Cr ...[more]