Ontology highlight
ABSTRACT:
SUBMITTER: Faustino I
PROVIDER: S-EPMC2941024 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Faustino Ignacio I Pérez Alberto A Orozco Modesto M
Biophysical journal 20100901 6
The structure and flexibility of the RNA duplex has been studied using extended molecular dynamics simulations on four diverse 18-mer oligonucleotides designed to contain many copies of the 10 unique dinucleotide steps in different sequence environments. Simulations were performed using the two most popular force fields for nucleic acids simulations (AMBER and CHARMM) in their latest versions, trying to arrive to a consensus picture of the RNA flexibility. Contrary to what was found for DNA dupl ...[more]