Comprehensive annotation of the transcriptome of the human fungal pathogen Candida albicans using RNA-seq.
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SUBMITTER: Bruno VM
PROVIDER: S-EPMC2945194 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
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Comprehensive annotation of the transcriptome of the human fungal pathogen Candida albicans using RNA-seq.
Bruno Vincent M VM Wang Zhong Z Marjani Sadie L SL Euskirchen Ghia M GM Martin Jeffrey J Sherlock Gavin G Snyder Michael M
Genome research 20100901 10
Candida albicans is the major invasive fungal pathogen of humans, causing diseases ranging from superficial mucosal infections to disseminated, systemic infections that are often lifethreatening. We have used massively parallel high-throughput sequencing of cDNA (RNA-seq) to generate a high-resolution map of the C. albicans transcriptome under several different environmental conditions. We have quantitatively determined all of the regions that are transcribed under these different conditions, an ...[more]
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