Ontology highlight
ABSTRACT:
SUBMITTER: Ahantarig A
PROVIDER: S-EPMC2946226 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Molecular biology reports 20080718 6
We have isolated and characterized the gene encoding a Drosophila melanogaster homolog of Caenorhabditis elegans UNC-51 (uncoordinated movement-51): Pegarn. Developmental Northern blot shows the Pegarn gene is expressed at all stages of development. The protein is detected throughout the Drosophila third instar larval central nervous system (CNS) in axons projecting out from the ventral ganglion and in the optic anlagen of the optic lobe. Heterozygous Pegarn mutant embryos show defects in larval ...[more]