Primary amyloidosis presenting as upper limb multiple mononeuropathies.
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ABSTRACT:
SUBMITTER: Tracy JA
PROVIDER: S-EPMC2947379 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
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Primary amyloidosis presenting as upper limb multiple mononeuropathies.
Tracy Jennifer A JA Dyck Peter J PJ Dyck P James B PJ
Muscle & nerve 20100501 5
Peripheral neuropathy in primary (AL) amyloidosis is usually lower-limb predominant, length-dependent, symmetrical, and affects small (pain and autonomic) fibers, as much or more than large fibers. We report a patient with stepwise progressive, multiple upper limb mononeuropathies that were due to nerve biopsy-proven primary amyloidosis (lambda light chain), with no systemic or autonomic features. Recognition that light chain amyloidosis may be the cause of a multiple mononeuropathy pattern adds ...[more]
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