A single qrr gene is necessary and sufficient for LuxO-mediated regulation in Vibrio fischeri.
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ABSTRACT:
SUBMITTER: Miyashiro T
PROVIDER: S-EPMC2947852 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
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A single qrr gene is necessary and sufficient for LuxO-mediated regulation in Vibrio fischeri.
Miyashiro Tim T Wollenberg Michael S MS Cao Xiaodan X Oehlert Dane D Ruby Edward G EG
Molecular microbiology 20100805 6
All members of the Vibrionaceae harbour LuxO, a response regulator that integrates outputs from various signalling systems, ultimately controlling specific traits that are crucial to the distinct biology of each species. LuxO is phosphorylated in response to low cell density, activating the transcription of a family of small RNAs called Qrrs, which in turn, control the levels of a global regulatory protein conserved within the Vibrionaceae. Although the function of each Qrr is similar, the numbe ...[more]
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