Changes in the vascular area fraction of the hippocampus and amygdala are induced by prenatal dexamethasone and/or adult stress.
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ABSTRACT:
SUBMITTER: Neigh GN
PROVIDER: S-EPMC2949211 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Publications
Changes in the vascular area fraction of the hippocampus and amygdala are induced by prenatal dexamethasone and/or adult stress.
Neigh Gretchen N GN Owens Michael J MJ Taylor W Robert WR Nemeroff Charles B CB
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100407 6
In addition to the neuronal and behavioral consequences of excess glucocorticoid exposure, the cerebrovascular system can also be adversely affected by stressors. This study determined that chronic stress in adulthood decreased the vascular area fraction of the hippocampus and increased the vascular area fraction of the amygdala. In addition, the data indicated that prenatal exposure to synthetic glucocorticoids modulated the effects of adult stress on vascular area fraction of the hippocampus a ...[more]
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