Ontology highlight
ABSTRACT:
SUBMITTER: Banneau G
PROVIDER: S-EPMC2949656 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Banneau Guillaume G Guedj Mickaël M MacGrogan Gaëtan G de Mascarel Isabelle I Velasco Valerie V Schiappa Renaud R Bonadona Valerie V David Albert A Dugast Catherine C Gilbert-Dussardier Brigitte B Ingster Olivier O Vabres Pierre P Caux Frederic F de Reynies Aurelien A Iggo Richard R Sevenet Nicolas N Bonnet Françoise F Longy Michel M
Breast cancer research : BCR 20100816 4
<h4>Introduction</h4>Breast carcinoma is the main malignant tumor occurring in patients with Cowden disease, a cancer-prone syndrome caused by germline mutation of the tumor suppressor gene PTEN characterized by the occurrence throughout life of hyperplastic, hamartomatous and malignant growths affecting various organs. The absence of known histological features for breast cancer arising in a PTEN-mutant background prompted us to explore them for potential new markers.<h4>Methods</h4>We first pe ...[more]