Ontology highlight
ABSTRACT:
SUBMITTER: Liu Z
PROVIDER: S-EPMC2950309 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Liu Zheng Z Sokka Tuulikki T Maas Kevin K Olsen Nancy J NJ Aune Thomas M TM
Human genomics and proteomics : HGP 20090427
In order to test the ability of peripheral blood gene expression profiles to predict future disease severity in patients with early rheumatoid arthritis (RA), a group of 17 patients (1 ± 0.2 years disease duration) was evaluated at baseline for gene expression profiles. Disease status was evaluated after a mean of 5 years using an index combining pain, global and recoded MHAQ scores. Unsupervised and supervised algorithms identified "predictor genes" whose combined expression levels correlated w ...[more]