Ontology highlight
ABSTRACT:
SUBMITTER: Mkhize NN
PROVIDER: S-EPMC2950605 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Mkhize Nonhlanhla N NN Gumbi Pamela P PP Liebenberg Lenine J LJ Ren Yuan Y Smith Peter P Denny Lynette L Passmore Jo-Ann S JA
Journal of virology 20100804 20
Initiation of highly active antiretroviral therapy (HAART) for HIV-infected individuals is associated with control of viremia, improved CD4 counts, and declining systemic HIV-specific immune responses. While HAART effectively reduces plasma viremia, it remains unclear how effectively antiretroviral drugs reach mucosal surfaces, such as those of the genital tract. The aim of this study was to determine the effect of HAART on genital tract CD4 T cell reconstitution, HIV shedding, and HIV-specific ...[more]