Ontology highlight
ABSTRACT:
SUBMITTER: Lee J
PROVIDER: S-EPMC2951142 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Bioorganic & medicinal chemistry 20080226 3
A small molecule inhibitor of alpha4 integrin-dependent cell migration was identified through a cell-based screen of small molecule libraries. Biochemical and cellular experiments suggest that this molecule functions by interacting with gamma-parvin. This molecule should serve as a useful tool to study alpha4 integrin signaling and may lead to new therapeutics for the treatment of autoimmune diseases. ...[more]