Post-translational modifications of microtubules.
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ABSTRACT:
SUBMITTER: Wloga D
PROVIDER: S-EPMC2951466 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Publications
Post-translational modifications of microtubules.
Wloga Dorota D Gaertig Jacek J
Journal of cell science 20101001 Pt 20
Microtubules--polymers of tubulin--perform essential functions, including regulation of cell shape, intracellular transport and cell motility. How microtubules are adapted to perform multiple diverse functions is not well understood. Post-translational modifications of tubulin subunits diversify the outer and luminal surfaces of microtubules and provide a potential mechanism for their functional specialization. Recent identification of a number of tubulin-modifying and -demodifying enzymes has r ...[more]
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