Ontology highlight
ABSTRACT:
SUBMITTER: Gottle M
PROVIDER: S-EPMC2951761 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Göttle Martin M Dove Stefan S Kees Frieder F Schlossmann Jens J Geduhn Jens J König Burkhard B Shen Yuequan Y Tang Wei-Jen WJ Kaever Volkhard V Seifert Roland R
Biochemistry 20100701 26
Cyclic adenosine 3',5'-monophosphate (cAMP) and cyclic guanosine 3',5'-monophosphate (cGMP) are second messengers for numerous mammalian cell functions. The natural occurrence and synthesis of a third cyclic nucleotide (cNMP), cyclic cytidine 3',5'-monophosphate (cCMP), is a matter of controversy, and almost nothing is known about cyclic uridine 3',5'-monophosphate (cUMP). Bacillus anthracis and Bordetella pertussis secrete the adenylyl cyclase (AC) toxins edema factor (EF) and CyaA, respectivel ...[more]