Ontology highlight
ABSTRACT:
SUBMITTER: Gorman J
PROVIDER: S-EPMC2953642 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Molecular cell 20071101 3
The ability of proteins to locate specific sites or structures among a vast excess of nonspecific DNA is a fundamental theme in biology. Yet the basic principles that govern these mechanisms remain poorly understood. For example, mismatch repair proteins must scan millions of base pairs to find rare biosynthetic errors, and they then must probe the surrounding region to identify the strand discrimination signals necessary to distinguish the parental and daughter strands. To determine how these p ...[more]