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New variants of known folds: do they bring new biology?


ABSTRACT: New distinct versions of known protein folds provide a powerful means of protein-function prediction that complements sequence and genomic context analysis. These structures do not supplant direct biochemical experiments, but are indispensable for the complete characterization of proteins.

SUBMITTER: Koonin EV 

PROVIDER: S-EPMC2954209 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature

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New variants of known folds: do they bring new biology?

Koonin Eugene V EV  

Acta crystallographica. Section F, Structural biology and crystallization communications 20100706 Pt 10


New distinct versions of known protein folds provide a powerful means of protein-function prediction that complements sequence and genomic context analysis. These structures do not supplant direct biochemical experiments, but are indispensable for the complete characterization of proteins. ...[more]

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