Odorant receptor polymorphisms and natural variation in olfactory behavior in Drosophila melanogaster.

ABSTRACT: Animals perceive and discriminate among a vast array of sensory cues in their environment. Both genetic and environmental factors contribute to individual variation in behavioral responses to these cues. Here, we asked to what extent sequence variants in six Drosophila melanogaster odorant receptor (Or) genes are associated with variation in behavioral responses to benzaldehyde by sequencing alleles from a natural population. Sequence analyses showed signatures of deviations from neutrality for Or42b and Or85f, and linkage disequilibrium analyses showed a history of extensive recombination between polymorphic markers for all six Or genes. We identified polymorphisms in Or10a, Or43a, and Or67b that were significantly associated with variation in response to benzaldehyde. To verify these ass

SUBMITTER: Rollmann SM 

PROVIDER: S-EPMC2954467 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature