Ontology highlight
ABSTRACT:
SUBMITTER: Kopec AK
PROVIDER: S-EPMC2955213 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Kopec Anna K AK Burgoon Lyle D LD Ibrahim-Aibo Daher D Burg Ashley R AR Lee Andrea W AW Tashiro Colleen C Potter Dave D Sharratt Bonnie B Harkema Jack R JR Rowlands J Craig JC Budinsky Robert A RA Zacharewski Timothy R TR
Toxicological sciences : an official journal of the Society of Toxicology 20100811 1
The toxic equivalency factor (TEF) approach recommended by the World Health Organization is used to quantify dioxin-like exposure concentrations for mixtures of polychlorinated dibenzo-dioxins, -furans, and polychlorinated biphenyls (PCBs), including 2,3,7,8-tetrachlorodibenzofuran (TCDF) and 3,3',4,4',5-pentachlorobiphenyl (PCB126) relative to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Whole-genome microarrays were used to evaluate the hepatic gene expression potency of TCDF and PCB126 relativ ...[more]