Ontology highlight
ABSTRACT:
SUBMITTER: Axarli I
PROVIDER: S-EPMC2956967 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Axarli Irene I Prigipaki Ariadne A Labrou Nikolaos E NE
Enzyme research 20100701
Bacterial cytochrome P450s (CYPs) constitute an important family of monooxygenase enzymes that carry out essential roles in the metabolism of endogenous compounds and foreign chemicals. In the present work we report the characterization of CYP102A2 from B. subtilis with a focus on its substrate specificity. CYP102A2 is more active in oxidation of sodium dodecyl sulphate (SDS) than any other characterized CYP. The effect of SDS and NADPH concentration on reaction rate showed nonhyperbolic and hyp ...[more]