Ontology highlight
ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC2959125 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Li Yongdong Y Yu Xiaolin X Ho Jeremy J Fushman David D Allewell Norma M NM Tuchman Mendel M Shi Dashuang D
Biochemistry 20100801 32
N-Acetyl-l-ornithine transcarbamylase (AOTCase), rather than ornithine transcarbamylase (OTCase), is the essential carbamylase enzyme in the arginine biosynthesis of several plant and human pathogens. The specificity of this unique enzyme provides a potential target for controlling the spread of these pathogens. Recently, several crystal structures of AOTCase from Xanthomonas campestris (xc) have been determined. In these structures, an unexplained electron density at the tip of the Lys302 side ...[more]