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(Anthracen-9-yl)(piperidin-1-yl)-methanone.

ABSTRACT: The title compound, C(20)H(19)NO, is a substructure of CP-640186, a potent inhibitor of mammalian acetyl-coenzyme A carboxyl-ases. In the crystal structure, the amide group forms a dihedral angle of 87.0?(1)° with the plane of the anthracene unit and the piperidine ring adopts a chair conformation. Mol-ecules are arranged into layers parallel to (100) and adjacent anthracene units within layers form dihedral angles of 13.2?(1)°. C-H?O inter-actions from the piperidine rings to the C=O group of the amide are observed between layers.

SUBMITTER: Hu HY

PROVIDER: S-EPMC2959661 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature

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(Anthracen-9-yl)(piperidin-1-yl)-methanone.

Hu Hua-You HY Huang Yu-Cheng YC Yu Hai-Tao HT Zhang Yan Y

Acta crystallographica. Section E, Structure reports online 20081015 Pt 11

The title compound, C(20)H(19)NO, is a substructure of CP-640186, a potent inhibitor of mammalian acetyl-coenzyme A carboxyl-ases. In the crystal structure, the amide group forms a dihedral angle of 87.0 (1)° with the plane of the anthracene unit and the piperidine ring adopts a chair conformation. Mol-ecules are arranged into layers parallel to (100) and adjacent anthracene units within layers form dihedral angles of 13.2 (1)°. C-H⋯O inter-actions from the piperidine rings to the C=O group of t ...[more]

PMID: 21580982

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