2-Methyl-2-(4-nitro-phen-oxy)propanoic acid.

ABSTRACT: The title compound, C(10)H(11)NO(5), is of inter-est with respect to its anti-dyslipidemic activity. It was prepared by reaction of 4-nitro-phenol with ethyl 2-bromo-2-methyl-propionate followed by ethyl ester hydrolysis. In the crystal, mol-ecules are linked into centrosymmetric dimers by inter-molecular O-H?O hydrogen bonds and the dimers are connected into chains by weak C-H?O inter-actions. The packing is further stabilized by offset ?-? inter-actions between adjacent benzene rings with a centroid-centroid distance of 3.8643?(17)?Å.

SUBMITTER: Navarrete-Vazquez G 

PROVIDER: S-EPMC2960050 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature