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Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra-hydro-pyrimidine-5-carboxyl-ate.


ABSTRACT: The title compound, C(14)H(16)N(2)O(3), belongs to a group of esters of 2-oxo- and 1,2,3,4-tetra-hydro-pyrimidine-5-carboxylic acids, which exhibit a wide spectrum of biological activities. The dihydro-pyrimidine ring adopts a screw-boat conformation. The crystal packing is stabilized by strong N-H?O and weak C-H?O inter-molecular hydrogen bonds. An intra-molecular C-H?O hydrogen bond is also present.

SUBMITTER: Nizam Mohideen M 

PROVIDER: S-EPMC2960668 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature

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Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra-hydro-pyrimidine-5-carboxyl-ate.

Nizam Mohideen M M   Rasheeth A A   Huq C A M A CA   Nizar S Syed SS  

Acta crystallographica. Section E, Structure reports online 20080813 Pt 9


The title compound, C(14)H(16)N(2)O(3), belongs to a group of esters of 2-oxo- and 1,2,3,4-tetra-hydro-pyrimidine-5-carboxylic acids, which exhibit a wide spectrum of biological activities. The dihydro-pyrimidine ring adopts a screw-boat conformation. The crystal packing is stabilized by strong N-H⋯O and weak C-H⋯O inter-molecular hydrogen bonds. An intra-molecular C-H⋯O hydrogen bond is also present. ...[more]

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