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(E)-(25S)-23-Acetyl-5?-furost-22-ene-3?,26-diol.

ABSTRACT: The title steroid, C(29)H(46)O(4), is a furostene derivative with a C=C double-bond length of 1.353?(3)?Å and an E configuration. The side chain is oriented toward the ? face of the A-E steroidal nucleus and presents a disordered terminal CH(2)-OH group [occupancies for resolved sites are 0.591?(9) and 0.409?(9)]. The methyl group at C20 attached to ring E is also oriented toward the ? face, avoiding steric hindrance with the carbonyl O atom of the acetyl group. The furostene and acetyl functionalities form an ?,?-unsaturated ketone system, with an s-cis configuration. All hydr-oxy and carbonyl groups are involved in weak inter-molecular hydrogen bonds. The absolute configuration was assigned from the synthesis.

SUBMITTER: Hernandez Linares MG

PROVIDER: S-EPMC2960791 | biostudies-literature |

REPOSITORIES: biostudies-literature

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Project description: Not available

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