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Racemic 4-(4-tert-butyl-phen-yl)-2,6-dimethyl-cyclo-hex-3-enecarboxylic acid.

ABSTRACT: The chirality of the title compound, C(19)H(26)O(2), is solely generated by the presence of the double bond in the cyclo-hexene ring. This compound was synthesized to study the inter-action of the two enanti-omers in the solid state. The resultant racemate is made up of carboxylic acid RS dimers. Inter-molecular O-H?O hydrogen bonds produce centrosymmetric R(2) (2)(8) rings which dimerize the two chiral enanti-omers through their carboxyl groups.

SUBMITTER: Xie S

PROVIDER: S-EPMC2960795 | biostudies-literature |

REPOSITORIES: biostudies-literature

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4-tert-Butyl-N-[(2,6-dimethyl-phen-yl)carbamothio-yl]benzamide.

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Project description:The title compound, C(16)H(20)O(2), was synthesized to study the hydrogen-bonding inter-action of the two enanti-omers in the solid state. The racemate is made up of carboxylic acid RS dimers. Inter-molecular O-H?O hydrogen bonds produce centrosymmetric R(2) (2)(8) rings which dimerize the two chiral enanti-omers through their carboxyl groups. The chirality of this compound is generated by the presence of the double bond in the cyclo-hexene ring and a chiral axis due to the meta-methyl substituent on the aromatic ring.

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