N-(2-Benzoyl-4-chloro-phen-yl)-4-chloro-benzene-sulfonamide.

ABSTRACT: The title compound, C(19)H(13)Cl(2)NO(3)S, is an N-aryl-sulfonyl derivative of 2-amino-5-chloro-benzophenone. The compound is biologically active and shows potential to be utilized as an inhibitor of CCR2 and CCR9 receptor functions. In the crystal structure, there is an intra-molecular N-H?O hydrogen bond between the amide and carbonyl groups. The benzoyl and 4-chloro-phenyl groups form intra-molecular and inter-molecular face-to-face contacts, with a dihedral angle of 10.6?(1)° between their mean planes in both cases, and centroid-centroid separations of 4.00?(1) and 4.25?(1)?Å for the intra- and inter-molecular inter-actions, respectively.

SUBMITTER: Valkonen A 

PROVIDER: S-EPMC2961035 | biostudies-literature | 2008 Mar

REPOSITORIES: biostudies-literature