Ontology highlight
ABSTRACT:
SUBMITTER: Peng X
PROVIDER: S-EPMC2962437 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Peng Xinxia X Gralinski Lisa L Armour Christopher D CD Ferris Martin T MT Thomas Matthew J MJ Proll Sean S Bradel-Tretheway Birgit G BG Korth Marcus J MJ Castle John C JC Biery Matthew C MC Bouzek Heather K HK Haynor David R DR Frieman Matthew B MB Heise Mark M Raymond Christopher K CK Baric Ralph S RS Katze Michael G MG
mBio 20101026 5
Studies of the host response to virus infection typically focus on protein-coding genes. However, non-protein-coding RNAs (ncRNAs) are transcribed in mammalian cells, and the roles of many of these ncRNAs remain enigmas. Using next-generation sequencing, we performed a whole-transcriptome analysis of the host response to severe acute respiratory syndrome coronavirus (SARS-CoV) infection across four founder mouse strains of the Collaborative Cross. We observed differential expression of approxima ...[more]