Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene.
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ABSTRACT:
SUBMITTER: Nguyen KT
PROVIDER: S-EPMC296263 | biostudies-literature | 2003 Dec
REPOSITORIES: biostudies-literature
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Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene.
Nguyen Kien T KT Tenor Jennifer J Stettler Hansruedi H Nguyen Lieu T LT Nguyen Liem D LD Thompson Charles J CJ
Journal of bacteriology 20031201 24
We identified adpA as an araC-like regulatory gene needed for colonial morphogenesis in Streptomyces coelicolor and showed that its activity depended on a unique TTA triplet corresponding to the leucyl-tRNA gene (bldA). These findings partially explained the dependence of aerial mycelium formation on a rare tRNA that is postulated to have developmental control functions. ...[more]
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