Hepatitis C virus experimental model systems and antiviral drug research.
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ABSTRACT:
SUBMITTER: Uprichard SL
PROVIDER: S-EPMC2963037 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Publications
Hepatitis C virus experimental model systems and antiviral drug research.
Virologica Sinica 20100728 4
An estimated 130 million people worldwide are chronically infected with hepatitis C virus (HCV) making it a leading cause of liver disease worldwide. Because the currently available therapy of pegylated interferon-alpha and ribavirin is only effective in a subset of patients, the development of new HCV antivirals is a healthcare imperative. This review discusses the experimental models available for HCV antiviral drug research, recent advances in HCV antiviral drug development, as well as active ...[more]
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