Ontology highlight
ABSTRACT:
SUBMITTER: Arnold PD
PROVIDER: S-EPMC2964163 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Arnold Paul Daniel PD Macmaster Frank P FP Hanna Gregory L GL Richter Margaret A MA Sicard Tricia T Burroughs Eliza E Mirza Yousha Y Easter Phillip C PC Rose Michelle M Kennedy James L JL Rosenberg David R DR
Brain imaging and behavior 20090301 1
This pilot study was undertaken to determine if there was a significant association between specific glutamate system genes and regional volumes of interest implicated in the pathogenesis of obsessive-compulsive disorder (OCD). Volumetric magnetic resonance imaging (MRI) and genotyping of 7 polymorphisms in two genes, glutamate receptor, ionotropic, N-methyl-d-aspartate 2B (GRIN2B) and solute linked carrier, family 1, member 1 (SLC1A1) were conducted in 31 psychotropic-naïve pediatric OCD patien ...[more]