Ontology highlight
ABSTRACT:
SUBMITTER: Conroy SA
PROVIDER: S-EPMC2965693 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
AIDS research and human retroviruses 20101006 10
HIV-1 subtype D (HIV-1D) progresses to disease faster and has lower transmissibility than subtype A (HIV-1A). We examined whether these differences could lead to a population level change in the distribution of these subtypes over time. HIV-1 viral RNA was extracted from stored serum samples from HIV-positive subjects participating in a population-based cohort study in Rakai, Uganda in 1994 and 2002. Portions of the viral proteins gag and gp41 were sequenced and subtyped. HIV-1 subtype assignmen ...[more]