Ontology highlight
ABSTRACT:
SUBMITTER: Thulasi P
PROVIDER: S-EPMC2966716 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Biochemistry 20101001 42
Relatively few thermodynamic parameters are available for RNA triloops. Therefore, 24 stem-loop sequences containing naturally occurring triloops were optically melted, and the thermodynamic parameters ΔH°, ΔS°, ΔG°(37), and T(M) for each stem-loop were determined. These new experimental values, on average, are 0.5 kcal/mol different from the values predicted for these triloops using the model proposed by Mathews et al. [Mathews, D. H., Disney, M. D., Childs, J. L., Schroeder, S. J., Zuker, M., ...[more]