Ontology highlight
ABSTRACT:
SUBMITTER: Chang HH
PROVIDER: S-EPMC2967743 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Chang Hsun-Hsien HH McGeachie Michael M Alterovitz Gil G Ramoni Marco F MF
BMC bioinformatics 20101028
<h4>Background</h4>Identification of expression quantitative trait loci (eQTLs) is an emerging area in genomic study. The task requires an integrated analysis of genome-wide single nucleotide polymorphism (SNP) data and gene expression data, raising a new computational challenge due to the tremendous size of data.<h4>Results</h4>We develop a method to identify eQTLs. The method represents eQTLs as information flux between genetic variants and transcripts. We use information theory to simultaneou ...[more]