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2-(5-Bromo-2-hydroxy-phen-yl)-1,2-dihydro-quinazolin-4(3H)-one.

ABSTRACT: The asymmetric unit of the title compound, C(14)H(11)BrN(2)O(2), contains two independent mol-ecules connected into a dimer by inter-molecular N-H?O hydrogen bonds involving the amine and carbonyl groups. The dimers are further connected by O-H?O hydrogen bonds, forming chains running parallel to the a axis, which are stabilized through ?-? stacking inter-actions, with a centroid-centroid distance of 3.679?(8)?Å. The dihedral angle between the two aromatic rings is 89.2?(4)°.

SUBMITTER: M Boghaei D

PROVIDER: S-EPMC2968101 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature

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2-(5-Bromo-2-hydroxy-phen-yl)-1,2-dihydro-quinazolin-4(3H)-one.

M Boghaei Davar D Najafpour Mohammad Mahdi MM McKee Vickie V McKee Vickie V

Acta crystallographica. Section E, Structure reports online 20081224 Pt 1

The asymmetric unit of the title compound, C(14)H(11)BrN(2)O(2), contains two independent mol-ecules connected into a dimer by inter-molecular N-H⋯O hydrogen bonds involving the amine and carbonyl groups. The dimers are further connected by O-H⋯O hydrogen bonds, forming chains running parallel to the a axis, which are stabilized through π-π stacking inter-actions, with a centroid-centroid distance of 3.679 (8) Å. The dihedral angle between the two aromatic rings is 89.2 (4)°. ...[more]

PMID: 21581648

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