N-(2,3-Dimethyl-phen-yl)-4-hydr-oxy-2-methyl-2H-1,2-benzothia-zine-3-carboxamide 1,1-dioxide.

ABSTRACT: In the crystal structure of the title compound, C(18)H(18)N(2)O(4)S, the thia-zine ring adopts a distorted half-chair conformation. 1,2-Benzothia-zines of this kind have a wide range of biological activities and are mainly used as medicines in the treatment of inflammation and rheumatoid arthritis. The enolic H atom is involved in an intra-molecular O-H?O hydrogen bond, forming a six-membered ring. The mol-ecules arrange themselves into centrosymmetric dimers by means of inter-molecular N-H?O hydrogen bonds. A weak inter-molcular C-H?O inter-action is also present.

SUBMITTER: Siddiqui WA 

PROVIDER: S-EPMC2968491 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature