Methyl trans-(±)-1-oxo-2-phenethyl-3-(thio-phen-2-yl)-1,2,3,4-tetra-hydro-isoquinoline-4-carboxyl-ate.

ABSTRACT: In the title compound, C(23)H(21)NO(3)S, the piperidine ring of the tetra-hydro-isoquinolinone unit adopts a screw-boat conformation. The thio-phene ring is disordered in a 0.700?(3):0.300?(3) ratio by an approximate 180° rotation of the ring around the C-C bond linking the ring to the tetra-hydro-isoquinolinone unit. The benzene ring of the tetra-hydro-isoquinolinone unit makes dihedral angles of 83.1?(2) and 62.38?(11)° with the major occupancy thio-phene ring and the phenyl ring, respectively. The dihedral angle between the phenyl ring and the thio-phene ring is 71.0?(2)°. In the crystal structure, mol-ecules are linked together by inter-molecular C-H?O and C-H?? inter-actions.

SUBMITTER: Akkurt M 

PROVIDER: S-EPMC2969771 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature