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Duloxetine hydro-chloride.

ABSTRACT: THE TITLE COMPOUND [SYSTEMATIC NAME: N-methyl-3-(1-naphth-yloxy)-3-(2-thien-yl)propan-1-aminium chloride], C(18)H(20)NOS(+)·Cl(-), was crystallized from 1,4-dioxane. Twofold rotational disorder exhibited by the thio-phene ring in a 0.580?(5):0.420?(5) ratio represents two different conformations of the mol-ecule that exist in the same crystal form. The crystal structure contains strong N-H?Cl hydrogen bonds.

SUBMITTER: Bhadbhade M

PROVIDER: S-EPMC2970009 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature

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Duloxetine hydro-chloride.

Bhadbhade Mohan M Hook James J Marjo Chris C Rich Anne A Lin Qinghong Q

Acta crystallographica. Section E, Structure reports online 20090829 Pt 9

THE TITLE COMPOUND [SYSTEMATIC NAME: N-methyl-3-(1-naphth-yloxy)-3-(2-thien-yl)propan-1-aminium chloride], C(18)H(20)NOS(+)·Cl(-), was crystallized from 1,4-dioxane. Twofold rotational disorder exhibited by the thio-phene ring in a 0.580 (5):0.420 (5) ratio represents two different conformations of the mol-ecule that exist in the same crystal form. The crystal structure contains strong N-H⋯Cl hydrogen bonds. ...[more]

PMID: 21577685

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