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Development of an automated microfluidic reaction platform for multidimensional screening: reaction discovery employing bicyclo[3.2.1]octanoid scaffolds.

ABSTRACT: An automated, silicon-based microreactor system has been developed for rapid, low-volume, multidimensional reaction screening. Use of the microfluidic platform to identify transformations of densely functionalized bicyclo[3.2.1]octanoid scaffolds will be described.

SUBMITTER: Goodell JR

PROVIDER: S-EPMC2976622 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature

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Development of an automated microfluidic reaction platform for multidimensional screening: reaction discovery employing bicyclo[3.2.1]octanoid scaffolds.

Goodell John R JR McMullen Jonathan P JP Zaborenko Nikolay N Maloney Jason R JR Ho Chuan-Xing CX Jensen Klavs F KF Porco John A JA Beeler Aaron B AB

The Journal of organic chemistry 20090801 16

An automated, silicon-based microreactor system has been developed for rapid, low-volume, multidimensional reaction screening. Use of the microfluidic platform to identify transformations of densely functionalized bicyclo[3.2.1]octanoid scaffolds will be described. ...[more]

PMID: 20560568

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