Ontology highlight
ABSTRACT:
SUBMITTER: Le Marchand L
PROVIDER: S-EPMC2978659 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Le Marchand Loïc L White Kami K KK Nomura Abraham M Y AM Wilkens Lynne R LR Selhub Jacob S JS Tiirikainen Maarit M Goodman Marc T MT Murphy Suzanne P SP Henderson Brian E BE Kolonel Laurence N LN
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20090801 8
B vitamins, such as folate, vitamin B6, and vitamin B12, play an important role as coenzymes in one-carbon metabolism and may affect colorectal cancer risk. We aimed to comprehensively investigate the relationships of plasma folate, pyridoxal-5'-phosphate (PLP, the active form of vitamin B6), vitamin B12, methylmalonic acid, homocysteine, and cysteine with colorectal cancer risk, accounting for suspected modifiers (alcohol intake, MTHFR C677T genotype, and plasma C-reactive protein) and potentia ...[more]