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2-(4-Fluoro-phen-yl)-N-{4-[6-(4-fluoro-phen-yl)-2,3-dihydro-imidazo[2,1-b][1,3]thia-zol-5-yl]pyridin-2-yl}acetamide.

ABSTRACT: In the crystal structure of the title compound, C(24)H(18)F(2)N(4)OS, the imidazole system makes dihedral angles of 34.3?(1) and 43.9?(1)°, respectively, with the directly attached 4-fluoro-phenyl and pyridine rings. The crystal structure is stabilized by inter-molecular N-H?N hydrogen bonding and by an intra-molecular C-H?O hydrogen inter-action. The F atom of the 2-(4-fluoro-phen-yl) group is disordered over two positions with site-occupancy factors of 0.75 and 0.25.

SUBMITTER: Selig R

PROVIDER: S-EPMC2979114 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature

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2-(4-Fluoro-phen-yl)-N-{4-[6-(4-fluoro-phen-yl)-2,3-dihydro-imidazo[2,1-b][1,3]thia-zol-5-yl]pyridin-2-yl}acetamide.

Selig Roland R Schollmeyer Dieter D Albrecht Wolfgang W Laufer Stefan S

Acta crystallographica. Section E, Structure reports online 20100421 Pt 5

In the crystal structure of the title compound, C(24)H(18)F(2)N(4)OS, the imidazole system makes dihedral angles of 34.3 (1) and 43.9 (1)°, respectively, with the directly attached 4-fluoro-phenyl and pyridine rings. The crystal structure is stabilized by inter-molecular N-H⋯N hydrogen bonding and by an intra-molecular C-H⋯O hydrogen inter-action. The F atom of the 2-(4-fluoro-phen-yl) group is disordered over two positions with site-occupancy factors of 0.75 and 0.25. ...[more]

PMID: 21579181

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